Nuclear Medicine Laboratory

 
Darya Ryzhkova, MD, DSc
Head of the research and clinical unit for nuclear medicine,
chief researcher at the nuclear cardiology research laboratory,
Professor of the RAS, board-certified radiologist

The Nuclear Medicine Laboratory is a part of the Radiology Unit.

Tasks:

  • Studying the diagnostic effectiveness of radionuclide methods in patients with diseases of internal organs.
  • Developing and implementing the modern radioisotope techniques, new radiopharmaceuticals and software applications for the processing of diagnostic and research data.
  • Participating in the implementation of comprehensive research projects in collaboration with other research and clinical units of the Centre and clinical testing.
  • Providing clinical guidance and assuring the quality of diagnostic activities of the clinical department for isotope diagnostics and positron emission tomography (PET).
  • Educational activity: professional development and advanced training of specialists in radiology, training of the academic staff in the postgraduate and PhD programs.

Major research areas:

  • Developing radiosynthesis methods and creating the quality standard for radiopharmaceuticals based on cyclotron and generator-produced positron-emitting isotopes
  • Enhancing the methods for preparation, development of optimal scanning protocols and implementation of radioisotope technologies for:
    — cardiac visualization to evaluate the perfusion, cardiac muscle metabolism, sympathetic innervation. Studying the pathogenesis of myocarditis and valvular heart disease using labeled biomarkers of inflammation and microcalcification of valves and vessels;
    — neuroimaging to detect brain and spinal cord neoplasms, areas of epileptic activity and pituitary microadenomas using various labeled compounds;
    — determining, staging and evaluating the effectiveness of treatment for malignant tumors of various sites;
    — diagnosing endocrine disorders, including the development of diagnostic algorithms for neuroendocrine tumors;
    — identifying the sites of infection and aseptic inflammation.
  • Developing and improving the protocols for radionuclide studies and computed tomography to reduce the exposure of patients and medical staff to ionizing radiation.

Major advances:

The specialists of the Laboratory published 85 articles in peer-reviewed journals, authored chapters for 7 monographs and handbooks, gave more than 200 conference presentations in Russian and abroad, filed 8 patents for inventions.

The Laboratory is engaged in international collaboration with PET centres of Turku (Finland) and Malmö (Sweden).

The Nuclear Medicine Laboratory, together with the departments for the production of radiopharmaceuticals, for quality control of radiopharmaceuticals, radioisotope imaging and PET, is a part of the research and clinical unit for nuclear medicine.