Scientists at the Research Laboratory of Molecular and Cellular Modeling and Gene Therapy of the WCRC for Personalized Medicine have completed a large part of research on the mechanisms of arrhythmogenesis in severe inherited disorders – laminopathies.
Laminopathies are a group of severe genetic disorders affecting various systems and organs. Laminopathies are one of the frequent causes leading to heart transplantation, and one of the most severe manifestations is the development of ventricular arrhythmias. In this regard, laminopathies became the first genetically determined condition, where the molecular basis of the diagnosis can contribute to the rationale for therapy and change the indications for the implantation of a cardioverter-defibrillator.
For more, read the news of the WCRC for Personalized Medicine.