Intellectual property

 

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Discoveries

Pattern of baroreflex regulation of blood pressure in mammals under emotional stress
Authors: Valdman A.V., Tsyrlin V.A., Shlyakhto E.V., Eremeev V.S., Bravkov M.F., Pliss M.G., Bershadsky B.G., Khrustaleva R.S., Scherbin Yu.V. Certificate for Discovery — Diploma No. 116 dated 21.05.1999.

Pattern of blood pressure regulation in humans and animals under the influence of baroreflex
Authors: Almazov V.A., Shlyakhto E.V., Kuzmenko N.V., Pliss M.G., Tsyrlin V.A., Scherbin Yu.I.
Certificate for Discovery – Diploma No. 400 dated 15.09.2010

Active patents

Patent for invention No. 2770787, registered on 21.04.2022, application No. 2021109991 dated 09.04.2021
“Method for personalized prediction of robot-assisted prostatectomy complexity based on prostate volume”
Authors: Mosoyan M.S., Fedorov D.A., Seredin I.E., Movsisyan A.T.

Patent for invention No. 2770785, registered on 21.04.2022, application No. 2021119259 dated 30.06.2021
“Method for detecting a form of cervical osteochondrosis in the late postoperative period”
Authors: Oleinik E.A., Oleinik A.A., Kudziev A.V., Nazarov A.S., Belyakov Yu.V., Ivanova N.E., Orlov A.Yu.

Patent for invention No. 2770120, registered on 14.04.2022, application No. 2021131920 dated 29.10.2021
“Method for treating hydronephrosis due to lower polar aberrant vessels strangulating the pyeloureteral segment”
Authors: Mosoyan M.S., Shanava G.Sh., Shelipanov D.A., Aisina N.A.

Patent for invention No. 2766800, registered on 15.03.2022, application No. 2021118780 dated 28.06.2021
“Method for transposition of the peroneal nerve in the upper third of the tibia”
Authors: Orlov A.Yu., Nazarov A.S., Kudziev A.V., Belyakov Yu.V., Oleinik E.A.

Patent for invention No. 2766245, registered on 10.02.2022, application No. 2021115638 dated 31.05.2021
“A method for suturing a right ventricular defect in intraventricular forms of myocardinal bridges of the coronary arteries”
Authors: Ismail-zade I.K., Grebennik V.K., Ivanov I.Yu., Gilfanov R.I., Gordeev M.L.

Patent for invention No. 2766251, registered on 10.02.2022, application No. 2021118376 dated 22.06.2021.
“Method for choosing a surgical access for off-pump supracoronary myotomy in patients with an isolated myocardial bridge of the anterior interventricular artery in the absence of other conditions requiring surgical treatment”
Authors: Ismail-zade I.K., Grebennik V.K., Ivanov I.Yu., Gilfanov R.I., Gordeev M.L.

Patent for invention No. 2762912, registered on 23.12.2021, application No. 2020137187 dated 11.11.2020
“Method for choosing a personalized general anesthesia technique for children in neurosurgical treatment”
Authors: Savvina I.A., Gurskaya V.I., Dryagina N.V., Aleksandrovich Yu.S.

Patent for invention No. 2762907, registered on 23.12.2021, application No. 2021117772 dated 16.06.2021
“Method for intraoperative differential diagnosis of morphological forms of congenital hyperinsulinism”
Authors: Perminova A.A., Mitrofanova L.B., Bairov V.G., Sukhotskaya A.A.

Patent for invention No. 2760242, registered on 23.11.2021, application No. 2021105348 dated 01.03.2021
“Method for assessing myocardial damage and the risk of complications after cardiopulmonary bypass heart surgery”
Authors: Dorofeikov V.V., Sheshurina T.A., Vavilova T.V.

Patent for invention No. 2758971, registered on 03.11.2021, application No. 2020143623 dated 28.12.2020
“Method for diagnosing obstructive uropathy in newborns and infants”
Authors: Bairov V.G., Sukhotskaya A.A., Ganiev Sh.S., Ovadyuk N.V.

Patent for invention No. 2755983, registered on 23.09.2021, application No. 2020113873 dated 03.04.2020
“Method for obtaining mineral-carbon sorbent based on granules of “Silochrome s-120” silica sorbent and its use as contact hemoactivator of blood cell components”
Authors: Kuznetsov S.I., Kirichuk O.P., Postnov V.N., Yuriev G.O., Burkova N.V., Romanchuk E.V., Sviridov E.E., Kiseleva A.D.

Patent for invention No. 2755690, registered on 20.09.2021, application No. 2021100562 dated 13.01.2021
“Method for detecting methicillin-resistance mecA and mecC genes in staphylococci”
Authors: Barantsevich E.P., Churkina I.V., Barantsevich N.E.

Patent for invention No. 2755581, registered on 17.09.2021, application No. 2021100722 dated 13.01.2021
“Method for personalized selection of surgical treatment for Morton’s neuroma”
Authors: Orlov A.Yu., Nazarov A.S., Belyakov Yu.V.

Patent for invention No. 2755579, registered on 17.09.2021, application No. 2020140664 dated 08.12.2020
“Method for the treatment of arm spasticity in patients with chronic disorders of consciousness”
Authors: Lesteva N.A., Kondratiev S.A., Kondratiev E.A., Vasiliev D.A., Zabolotsky D.V., Kondratiev A.N.

Patent for invention No. 2754386, registered on 01.09.2021, application No. 2020134503 dated 20.10.2020
“Method for decompression of the median nerve at the level of the carpal ligament”
Authors: Orlov A.Yu., Nazarov A.S., Kudziev A.V., Belyakov Yu.V., Gorodnina A.V.

Patent for invention No. 2754300, registered on 31.08.2021, application No. 2020133895 dated 14.10.2020
“Method for predicting the antiarrhythmic efficacy of myocardial revascularization surgery in patients with coronary artery disease with ventricular arrhythmias provoked by myocardial ischemia”
Authors: Treshkur T.V., Tatarinova A.A., Ryngach E.A.

Patent for invention No. 2754059, registered on 25.08.2021, application No. 2021105347 dated 01.03.2021
“Method for assessing the state of the central nervous system in patients with postmastectomy syndrome”
Authors: Pospelova M.L., Bukkieva T.A., Efimtsev A.Yu., Fionik O.V., Efimova M.Yu., Alekseeva T.M., Ivanova N.E., Trufanov G.E., Lepekhina A.S., Levchuk A.G., Gorbunova E.A., Samochernykh K.A., Krasnikova V.V., Kasumova A.A.

Patent No. 2752747, registered on 02.08.2021, application No. 2020132580 dated 01.10.2020
“Method for the treatment of trophic skin disorders in patients with severe brain damage”
Authors: Kondratiev A.N., Kondratiev E.A., Lesteva N.A., Kondratiev S.A., Zabrodskaya Yu.M., Rybakov G.Yu., Chirkova O.A., Sergienko S.K.

Patent for invention No. 2750713, registered on 01.07.2021, application No. 2020134504 dated 20.10.2020
“Method for treatment of juvenile hypogonadotropic hypogonadism in experiment”
Authors: Nikitina I.L., Bayramov A.A., Yukhlina Yu.N., Shabanov P.D., Galagudza M.M., Grineva E.N., Droblenkov A.V., Masel A.S., Zelener A.O., Sarakaeva L.R., Plaksina A.O.

Patent No. 2749480, registered on 11.06.2021, application No. 2020130471 dated 15.09.2020
“Method for surgical treatment of metastatic lesions of the lumbar spine”
Authors: Orlov A.Yu., Nazarov A.S., Kudziev A.V., Belyakov Yu.V.

Patent No. 2749477, registered on 11.06.2021, application No. 2020113871 dated 03.04.2020
“Method for modeling male hypogonadotropic hypogonadism”
Authors: Bayramov A.A., Nikitina I.L., Yukhlina Yu.N., Grineva E.N., Shabanov P.D., Galagudza M.M., Kelmanson I.A., Masel A.S., Zelener A.O., Sarakaeva L.R., Plaksina A.O.

Patent No. 2747661, registered on 11.05.2021, application No. 2020123114 dated 07.07.2020
“Method for assessing the radicality of exclusion of cerebral arteriovenous malformations from the blood flow”
Authors: Rozhchenko L.V., Dryagina N.V.

Patent No. 2747657, registered on 11.05.2021, application No. 2020129159 dated 02.09.2020
“Method for treatment of high-flow arterio-sinus fistulas of the brain with an isolated sinus”
Authors: Petrov A.E., Rozhchenko L.V.

Patent No. 2746435, issued on 14.04.2021, application No. 2020113872 dated 03.04.2020
“Method for modeling an infected wound in SPF rats”
Authors: Galagudza M.M., Toropova Ya.G., Belsky Yu.P., Belskaya N.V.

Patent No. 2744680 issued on 15.03.2021, application No. 2020120620 dated 16.06.2020
“Method for predicting the development of postpartum endometritis”
Authors: Batrakova T.V., Zazerskaya I.E., Vavilova T.V., Dolgo-Saburova Yu.V., Osipova N.A.

Patent No. 2743810 issued on 26.02.2021, application No. 2020124241 dated 14.07.2020
“Method for initiating physiological reverse myocardial remodeling by personalized selection of the aerobic training intensity in patients with chronic heart failure”
Authors: Lelyavina T.A., Sitnikova M.Yu., Galenko V.L., Bortsova M.A.

Patent No. 2743806 issued on 26.02.2021, application No. 2020121918 dated 26.06.2020
“Method for predicting the development of infectious complications and sepsis in patients with severe traumatic brain injury”
Authors: Savvina I.A., Sebelev K.I., Zabrodskaya Yu.M., Bodareva N.V., Lavrinenko N.V., Tkebuchava I.V.

Patent No. 2743802 issued on February 26, 2021, application No. 2020125961 dated 29.07.2020
Method for determining universal indices of fractional anisotropy of the frontal and temporal lobar neocortex for the early diagnosis of vascular dementia
Authors: Trufanov G.E., Levashkina I.M., Serebryakova S.V., Medenikov A.A., Efimtsev A.Yu., Mashchenko I.A.

Patent No. 2742367 issued on 05.02.2021, application No. 2020121919 dated 26.06.2020
“Method for safe exposure of the renal pedicle vessels during endovideosurgical resection of the kidney and radical nephrectomy in laparoscopic and robot-assisted procedures”
Authors: Mosoyan M.S., Fedorov D.A., Gilev E.S.

Patent No. 2742254 issued on 04.02.2021, application No. 2020132345 dated 29.09.2020
“Method for surgical treatment of chronic subdural hematomas”
Authors: Petrov A.E., Rozhchenko L.V., Ivanov A.A.

Patent No. 2741717 issued on 28.01.2021, application No. 2020113870 dated 03.04.2020
“Method of hemostasis in the surgical treatment of renal cell carcinoma”
Authors: Mosoyan M.S., Fedorov D.A., Gilev E.S.

Patent No. 2738769 issued on 16.12.2020, application No. 2020130468 dated 15.09.2020
“Artificial lung ventilation apparatus”
Author: Znamensky V.A.

Patent No. 2735127 issued on 28.10.2020, application No. 2019127820 dated 03.09.2019
“Method for transpedicular fixation of the lumbar spine”
Authors: Gulyaev D.A., Godanyuk D.S., Belov I.Yu., Kurnosov I.A.

Patent No. 2735080 issued on 28.10.2020, application No. 2018146344 dated 24.12.2018
“Agent based on water-soluble plant polysaccharides enhancing nitric oxide secretion by macrophages in vitro”
Authors: Danilets M.G., Avdeeva E.Yu., Ligacheva A.A., Reshetov Ya.E., Guryev A.M., Trofimova E.S., Sherstoboev E.Yu., Belousov M.V., Yusubov M.S., Rovkina K.I., Krivoschekov S.V., Belsky Yu.P., Belskaya N.V.

Patent No. 2734994 issued on 27.10.2020, application No. 2020101137 dated 10.01.2020
“Method for determining the hemodynamic significance of stenosis of the internal carotid artery”
Authors: Semenyutin V.B., Nikiforova A.A., Panuntsev G.K., Aliev V.A.

Patent No. 2733684 issued on 06.10.2020, application No. 2019117251 dated 03.06.2020
“Method for surgical treatment of high-flow arteriovenous fistulas in the structure of cerebral arteriovenous malformations”
Authors: Petrov A.E., Goroschenko S.A., Rozhchenko L.V.

Patent No. 2732707 issued on 21.09.2020, application No. 2020101135 dated 10.01.2020
“Method for robot-assisted laparoscopic radical prostatectomy with lateral fixation of the bladder neck in the treatment of prostate cancer”
Authors: Mosoyan M.S., Fedorov D.A., Vasiliev A.A.

Patent No. 2732215 issued on 14.09.2020, application No. 2019145499 dated 27.12.2019
“Technique of supracoronary myotomy”
Authors: Ismail-zade I.K., Grebennik V.K., Schumacher R.S., Gordeev M.L.

Patent No. 2730983 issued on 26.08.2020, application No. 2019118525 dated 14.06.2019
“Method for bifurcated stent-graft implantation into the infrarenal aorta”
Authors: Zvereva E.D., Zverev D.A., Gordeev M.L.

Patent No. 2730955 issued on 26.08.2020, application No. 2019139121 dated 29.11.2019
“Method for reconstruction of the anterior cranial fossa base when performing block resection of a disseminated tumor of the anterior skull base”
Authors: Primak N.A., Gulyaev D.A., Belov I.Yu., Nechaeva A.F.

Patent No. 2730927 issued on 26.08.2020, application No. 2019139122 dated 29.11.2019
“Method for plastic closure of a defect in the internal auditory canal after resection of the intracanal part of vestibular schwannomas”
Authors: Primak N.A., Gulyaev D.A., Belov I.Yu., Nechaeva A.F.

Patent No. 2728591 issued on 30.07.2020, application No. 2019130692 dated 26.09.2019
“Method for predicting the antiarrhythmic efficacy of beta-blockers in pregnant women with high-grade ventricular arrhythmias without structural heart disease”
Author: Treshkur T.V., Bernhardt E.R., Zazerskaya I.E., Popov S.V.

Patent No. 2725853 issued on 06.07.2020, application No. 2019125066 dated 06.08.2019
“Method for simultaneous bilateral catheterization of the cavernous and inferior petrosal sinuses with venous blood sampling to measure the level of adrenocorticotropic hormone and prolactin”
Authors: Rudakov I. A., Savello A. V., Cherebillo V. Yu., Tsoi U. A., Grineva E. N., Kuritsyna N. V.

Patent No. 2725852 issued on 06.07.2020, application No. 2019127940 dated 04.09.2019
“Robot-assisted laparoscopic radical prostatectomy with posterior pelvic reconstruction in the treatment of prostate cancer”
Authors: Mosoyan M.S., Fedorov D.A.

Patent No. 2725851 issued on 06.07.2020, application No. 2019112158 dated 22.04.2019
“Method of modified right ventricle outflow tract reconstruction with preservation of the own pulmonary valve in the radical correction for tetralogy of Fallot”
Authors: Kozyrev I.A., Morozov A., Latypov A.K.

Patent No. 2722454 issued on 01.06.2020, application No. 2019140321 dated 06.12.2019
“Method for determining the risk of repeat myocardial revascularization in patients with coronary artery disease after percutaneous coronary intervention with stenting”
Author: Polyakova E.A., Biryukov A.V., Berkovich O.A., Baranova E.I., Shlyakhto E.V.

Patent No. 2716596 issued on 13.03.2020, application No. 2019128217 dated 06.09.2019
“Method for reducing the size of myocardial ischemia/reperfusion injury using quinacrine”
Authors: Sonin D.L., Pochkaeva E.I., Papayan G.V., Petrishchev N.N., Zaitseva E.A., Novruzova K.K., Volobuev E.Yu., Galagudza M.M.

Patent No. 2716507 issued on 12.03.2020, application No. 2019125067 dated 06.08.2019
“Method for intraoperative neurophysiological monitoring of motor and speech areas of the brain”
Authors: Zharova E.N., Gulyaev D.A., Savvina I.A., Lakhina Yu.S., Petrov A.A., Vaskova N.L.

Patent No. 2716463 issued on 11.03.2020, application No. 2019134768 dated 29.10.2019
“Robot-assisted laparoscopic radical prostatectomy with anterior pelvic reconstruction in the treatment of prostate cancer”
Authors: Mosoyan M.S., Fedorov D.A., Gilev E.S.

Patent No. 2716457 issued on 11.03.2020, application No. 2019112269 dated 22.04.2019
“Method of implantation of C2 fixation screws in the surgical treatment of craniovertebral instability”
Authors: Godanyuk D.S., Gulyaev D.A., Biragov D.V.

Patent No. 2716455 issued on 11.03.2020, application No. 2019125445 dated 27.05.2019
“Method of balloon angioplasty of pulmonary artery branches in patients with chronic thromboembolic pulmonary hypertension”
Authors: Marukyan N.V., Simakova M.A., Moiseeva O.M., Zverev D.A., Zubarev D.D.

Patent No. 2716453 issued on 11.03.2020, application No. 2019108904 dated 27.03.2019
“Method for hybrid treatment of aortic aneurysm without cardiopulmonary bypass with maintenance of cerebral perfusion during transposition of the aortic arch branches”
Authors: Shlomin V.V., Bondarenko P.B., Puzdryak P.D., Gusinsky A.V., Fionik O.V., Gordeev M.L.

Patent No. 2713592 issued on 05.02.2020, application No. 20019103465 dated 07.02.2019
“Method for controlling the residual interventricular septal thickness during septal myectomy”
Authors: Gurshchenkov A.V., Selivanov M.V., Mukhin E.A., Agaev R.S., Dyachenko Ya.A., Maistrenko A.D., Gordeev M.L.

Patent No. 2713436 issued on 05.02.2020, application No. 2019130693 dated 26.09.2019
“Method for the differential diagnosis of isolated preeclampsia and preeclampsia associated with undiagnosed chronic arterial hypertension”
Authors: Bettiher O.A., Zazerskaya I.E., Bart V.A., Ryabokon N.R.

Patent No. 2712630 issued on 30.01.2020, application No. 2019115702 dated 22.05.2019
“Use of sorbent granules from super-cross-linked polystyrene «Stirosorb 516» as a contact hemoactivator of blood cell elements”
Authors: Kuznetsov S.I., Kirichuk O.P., Burkova N.V., Davankov V.A., Romanchuk E.V., Kiseleva A.D., Sviridov E.E.

Patent No. 2712626 issued on 30.01.2020, application No. 2019120307 dated 27.06.2019
“Use of granules of silica sorbent Silochrome C-120 as a contact hemoactivator of blood cell elements”
Authors: Kuznetsov S.I., Kirichuk O.P., Burkova N.V., Postnov V.N., Yuriev G.O., Romanchuk E.V.

Patent No. 2708058 dated 03.12.2019
Method for choosing the surgical tactics for ophthalmic segment carotid artery aneurysms when the ophthalmic artery is involved in the structure of the aneurysm or associated with it (Russian Inventions)

Patent No. 2707377 dated 26.11.2019
Method for intraoperative imaging of suture failure during sleeve gastrectomy (Russian Inventions)

Patent No. 2707141 dated 22.11.2019
Method for predicting the probability of detecting true ventricular tachyarrhythmia in patients with implanted devices for the primary prevention of sudden cardiac death (Russian Inventions)

Patent No. 2706382 dated 18.11.2019
Method for the combination treatment of patients with ischemic stroke in the acute stage and during early rehabilitation using infrared terahertz radiation (Russian Inventions)

Patent No. 2701722 dated 01.10.2019
Method for assessing the activation capabilities of blood contact preparations (including sorbents) by the adhesion rate of blood cells (Russian Inventions)

Patent No. 2699218 dated 03.09.2019
Method for diagnosing MRI-negative ACTH-secreting pituitary adenomas (Russian Inventions)

Patent No. 2697230 dated 13.08.2019
Method for predicting recovery of consciousness in patients in a vegetative state of non-traumatic genesis based on the analysis of the dynamics of the background bioelectric activity of the brain after the use of zolpidem (Russian Inventions)

 

Patent No. 2696937 dated 07.08.2019
Method for determining autonomic nervous system imbalance in patients with ventricular arrhythmia caused by psycho-emotional factors without structural heart disease (Russian Inventions)

 

Patent No. 2695355 dated 23.07.2019
Method for managing cognitive disorders in ICU patients with septic encephalopathy (Russian Inventions)

 

Patent No. 2694544 dated 16.07.2019
Method for preventing the development of infectious complications and sepsis in neurosurgical patients with aneurysmal disease of the cerebral vessels in the acute stage of aneurysm rupture. Options. (Russian Inventions)

 

Patent No. 2694509 dated 15.07.2019
Hydrodynamic test bench for studying the permeability of vessel walls for magnetic nanoparticles under the influence of an external magnetic field (Russian Inventions)

 

Patent No. 2693450 dated 02.07.2019
Method of subcutaneous ulnar nerve transposition to the anterior surface of the forearm (Russian Inventions)

 

Patent No. 2692324 dated 24.06.2019
Method for plastic surgery of a surgical defect after subtotal block resection of the temporal bone pyramid (Russian Inventions)

 

Patent No. 2692247 dated 24.06.2019
Method for the treatment of post-operative delirium (Russian Inventions)

 

Patent No. 2687879 dated 16.05.2019
Method for surgical treatment of parasellar tumors with invasion into the optic nerve canal (Russian Inventions)

 

Patent No. 2687787 dated 16.05.2019
Method for surgical treatment of aortic coarctation combined with distal aortic arch hypoplasia (Russian Inventions)

 

Patent No. 2687777 dated 16.05.2019
Method for spondylodesis in the region of craniovertebral junction and the upper cervical spine with blood-supplied autologous grafts (Russian Inventions)

 

Patent No. 2687021 dated 06.05.2019
Method for removing a blastomatous tumor in the mediobasal regions of the temporal lobe and/or thalamus (Russian Inventions)

 

Patent No. 2686736 dated 30.04.2019
Method for detecting intraoperative complications in neurosurgical patients (Russian Inventions)

 

Patent No. 2679656 dated 12.02.2019
Method for detecting the macroforms of creatine kinase and MB-isoenzyme in human blood serum (Russian Inventions)

 

Patent No. 2678686 dated 30.01.2019
Method for preparing the pulmonary circulation of recipients before heart transplantation (Russian Inventions)

 

Patent No. 2678685 dated 30.01.2019
Method for registering the linear velocity of blood flow in the internal carotid artery (Russian Inventions)

 

Patent No. 2675353 dated 18.12.2018
Method for modeling chronic thromboembolic pulmonary hypertension (Russian Inventions)

 

Patent No. 2675067 dated 14.12.2018
Method for predicting the symptomatic relapse of coronary artery disease using neural networks in patients after endovascular procedure (Russian Inventions)

 

Patent No. 2666942 dated 13.09.2018
Method for the treatment of polyneuromyopathy of critical conditions in intensive care patients (Russian Inventions)

 

Patent No. 2649506 dated 03.04.2018
Method for determining the electroanatomical substrate in high-density contact mapping of the left atrial endocardial surface to stratify the risk of atrial fibrillation recurrence after circular pulmonary vein isolation in patients with paroxysmal and persistent atrial fibrillation (Russian Inventions)

 

Patent No. 2647622 dated 16.03.2018
Method for choosing individual premedication in the structure of anesthetic support (Russian Inventions)

 

Patent No. 2629019 dated 24.08.2017
Method for intraoperative prevention of local ischemic brain damage during microsurgery for cerebral arterial aneurysms (Russian Inventions)

 

Patent No. 2548801 dated 20.04.2015
Method for assessing the angiogenic potential of progenitor cells in patients with cardiovascular diseases (Russian Inventions)

Foreign patents

Certificate WDTS-PC-00002664, registered on 14.12.2021
Educational module of Further education “Fundamentals of Scientific Management”
Authors: Konradi A.O., Starshinova A.A., Mulyukha V.M., Dyshlyuk M.V., Revkova E.G., Arkhipenko E.V., Nechaeva E.A., Malkova A.M., Andreeva A.V.

German utility model patent No. 016668.6 dated 22.04.2010
Method for determining the antithrombotic effect of acetylsalicylic acid
Authors: Ivanov V. I., Dorofeikov V. V., Vavilova A. V.