Research Department of Microcirculation and Myocardial Metabolism


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Dmitry Sonin, MD, PhD
Head of Department

The Research Department of Microcirculation and Myocardial Metabolism was established in 2016 as part of the Centre for Experimental Biomodeling. It was composed of the Microcirculation Research Laboratory and Myocardial Metabolism Research Laboratory.

Major topics and ongoing projects

  • Improving the efficiency of pharmacological cardiас protection using nanoscale drug carriers. As part of this topic, the Department is investigating the efficacy of cardiac protection using targeted drug delivery of mast cell stabilizers to attenuate myocardial ischemia reperfusion injury.
  • Improving the efficiency of pharmacological cardiас protection using nanoscale drug carriers.
  • Developing a strategy for myocardial protection against ischemia/reperfusion injury based on a controlled change in the composition of the gut microbiota.
  • Studying metabolic and systemic effects of various types of bariatric surgery in type 2 diabetes mellitus.
  • Studying the effect of various types of bariatric surgery on the endothelium and myocardial resistance to infarction in an experiment on euglycemic animals without obesity modeling.
  • Developing a model for intravital video microimaging of the vascular bed with measurement of the diameter of the vessels.
  • Developing a technique for heterotopic heart transplantation in rodents.

Major research areas

Research is carried out in close collaboration with other laboratories of the Institute of Experimental Medicine as well as scientific and clinical units of Almazov Centre.

Major areas include:

  • Myocardial protection against ischemia/reperfusion injury by pre- and postconditioning in the experiment and clinical practice
  • Development of methods for targeted drug delivery to the ischemic myocardium using nanocarriers
  • Pharmacological and non-pharmacological cerebral protection against ischemia/reperfusion injury
  • Study of mechanisms and methods for assessing brain damage in rat stroke models
  • Stimulation of myocardial regeneration after injury by activating the differentiation of resident progenitor cells and mesenchymal stem cells
  • Optimization of surgical approaches to repair metabolic disorders in type 2 diabetes mellitus in the experimental model of diabetes mellitus and in patients with type 2 diabetes mellitus and BMI of 30–35 kg/m2
  • Studying the pathophysiology of microcirculation and hemostasis
  • Development of fluorescence imaging methods for ischemia and other forms of tissue damage
  • Development of new cardioplegic solutions
  • Development of new organ preservation solutions for donor heart and donor kidney
  • Development of methods for reconditioning and preservation of a donor heart obtained from an asystolic donor

State assignments

Since 2021, the specialists of the Research Department of Microcirculation and Myocardial Metabolism have been carrying out applied research and experimental development under state assignments jointly with other departments of Almazov Centre.

  • «Search for apoptosis-inducing compounds as candidates for drugs with antitumor activity and a new mechanism of action» (registration number 121031100309-7, supervised by Yu. Belsky).
  • “Creation of a new experimental model of a normotrophic pseudoarthrosis using a composite material based on hydroxyapatite and a copolymer of lactide and glycolide” (registration number 121031100312-7, supervised by A. Karpov).
  • «Development of technology for the manufacture of liposomal forms of cardiac protectors for targeted drug delivery to the myocardium» (registration number 121031100308-0, supervised by D. Korolev).
  • “Development of approaches for binding and inactivation of the SARS-CoV-2 virus in the body of a COVID-19 patient and extracorporeally using genetically engineered recombinant proteins” (registration number 121031100284-7, supervised by Yu. Cheburkin).
  • «Development and preclinical testing of fluorescence imaging technologies for pathological processes in surgery» (2016—2019, supervised by M. Galagudza).


In 2021, the specialists carried out research under the following grants:

  • Grant for a major scientific project of the Russian Ministry of Science and Higher Education No. 075-15-2020-800 on the topic «Development of new neuromodulation-based technologies for heart failure prevention and treatment» (supervised by M. Galagudza)
  • Grant of the Russian Science Foundation No. 18-15-00153 for basic and exploratory research on the topic «Development of a strategy for myocardial protection against ischemia/reperfusion injury based on a controlled change in the composition of gut microbiota» (supervised by M. Galagudza)
  • RFBR grant No. 20-015-00552 for basic research on the topic “Investigation of the mechanisms of the effect of hypothermic conditioning on the state of the myocardium and the microcirculation of the donor heart obtained from an asystolic donor” (supervised by M. Galagudza)

Other grants

  • Grant of the Russian Science Foundation, topic: «Myocardial protection against ischemia/reperfusion injury by targeted delivery of cardioprotective substances» (2014–2017, supervised by M. Galagudza, agreement No. 14-15-00473).
  • Grant of the Russian Science Foundation, topic: «Development of personalized therapy for obesity and diabetes mellitus in order to reduce cardiovascular risks» (2017–2020, E. Shlyakhto, agreement No. 17-75-30052).
  • Grant of the Russian Science Foundation, topic: «Development of a strategy for myocardial protection against ischemia/reperfusion injury based on a controlled change in the composition of gut microbiota» (2018–2020, supervised by M. Galagudza, agreement No. 18-15-00153).

State assignments

«Development and preclinical testing of technologies for fluorescence imaging of pathological processes in surgery» (2016—2019, supervised by M. Galagudza).

Key achievements and results

Ongoing research and development prospects

Participation in scientific programs


The Research Department of Microcirculation and Myocardial Metabolism has many years of cooperation with leading universities and research institutions of St. Petersburg and Moscow, including St. Petersburg State University, Peter the Great St. Petersburg Polytechnic University, Pavlov First State Medical University, ITMO University, National Medical Research Radiology Center, Moscow State University of Fine Chemical Technologies, Moscow Technological University, Sechenov Institute of Evolutionary Physiology and Biochemistry, etc.

International collaboration includes projects with the University of Oslo (Norway) and the University of Iowa (USA).

International collaboration

Memorandum of Understanding with the University of Oslo (Norway) targets to develop cooperation in the field of experimental medicine and molecular biology.

Major publications


Kaljusto ML, Bautin A, Jakobsen Ø, Wilimski R, Brunborg C, Wennemo M, Karpova L, Nergaard Aas K, Arendarczyk A, Landsverk SA, Galagudza M, Næsheim T, Czub P, Gordeev M, Vaage J. Effects of ischaemic postconditioning in aortic valve replacement: a multicenter randomized controlled trial. Eur J Cardiothorac Surg. 2022 May 2;61 (5):1144—1152. Access link:

Karpov AA, Vaulina DD, Smirnov SS, Moiseeva OM, Galagudza MM. Rodent models of pulmonary embolism and chronic thromboembolic pulmonary hypertension. Heliyon. 2022 Feb 24;8 (3):e09014. Access link:

Korolev DV, Shulmeyster GA, Istomina MS, Evreinova NV, Aleksandrov IV, Krasichkov AS, Postnov VN, Galagudza MM. Fluorescently Labeled Gadolinium Ferrate/Trigadolinium Pentairon (III) Oxide Nanoparticles: Synthesis, Characterization, In Vivo Biodistribution, and Application for Visualization of Myocardial Ischemia-Reperfusion Injury. Materials (Basel). 2022 May 27;15 (11):3832. Access link:

Korolev DV, Shulmeyster GA, Evreinova NV, Syrovatkina MS, Istomina MS, Postnov VN, Aleksandrov IV, Krasichkov AS, Galagudza MM. Theranostic Platforms Based on Silica and Magnetic Nanoparticles Containing Quinacrine, Chitosan, Fluorophores, and Quantum Dots. Int J Mol Sci. 2022 Jan 15;23 (2):932. Access link:

V. Mamontov, A. A. Karpov, S. M. Minasian, D. A. Fedoseeva, A. N. Kalinichenko and A. A. Kamshilin, «Physical Training Reverses the Impaired Cardiac Autonomic Control and Exercise Tolerance Induced by Right-Side Vagal Denervation,» in IEEE Access, vol. 10, pp. 10393-10401, 2022. Access link:


Kornyushin O. V., Sonin D. L., Polozov A. S., Masley V. V., Istomina M. S., Papayan G. V., Mukhametdinova D. V., Cheburkin Yu. V., Toropova Ya. G., Zelinskaya I. A., Neimark A. E., Derkach K. V., Shpakov A. O., Galagudza M. M. Effects of three types of bariatric interventions on myocardial infarct size and vascular function in rats with type 2 diabetes mellitus. Life Sciences. 2021; 279: 119676 1-11. IF IF 6,78. Access link:

Karpov A. A., Anikin N. A., Mihailova A. M., Smirnov S. S., Vaulina D. D., Shilenko L. A., Ivkin D. Yu., Bagrov A. Y., Moiseeva O. M., Galagudza M. M… Model of Chronic Thromboembolic Pulmonary Hypertension in Rats Caused by Repeated Intravenous Administration of Partially Biodegradable Sodium Alginate Microspheres. International Journal of Molecular Sciences. 2021; 22 (3): 1149 1-17. IF 6,208. Access link:

Deryabin P., Domnina A., Gorelova I., Rulev M., Petrosyan M., Nikolsky N., Borodkina A. “All-In-One” Genetic Tool Assessing Endometrial Receptivity for Personalized Screening of Female Sex Steroid Hormones. Frontiers in Cell and Developmental Biology. 2021; 9: 624053 1-15. IF 6,081. Access link:

Dmitry Korolev, Michael Shumilo,  Galina Shulmeyster,  Alexander Krutikov,  Alexey Golovkin,  Alexander Mishanin,  Andrew Gorshkov,  Anna Spiridonova,  Anna Domorad,  Alexander Krasichkov,  Michael Galagudza. Hemolytic Activity, Cytotoxicity, and Antimicrobial Effects of Human Albumin- and Polysorbate-80-Coated Silver Nanoparticles. 2021; 11 (6): 1484 1-20. IF 5,719. Access link:

Simanenkova A., Minasian S., Karonova T., Vlasov T., Timkina N., Shpilevaya O., Khalzova A., Shimshilashvili A., Timofeeva V., Samsonov D., Borshchev Yu., Galagudza M. Comparative evaluation of metformin and liraglutide cardioprotective effect in rats with impaired glucose tolerance. Scientific Reports. 2021; 11: 6700 1-12. IF 5,516. Access link:

Polyakova E.A., Mikhaylov E.N., Sonin D.L., Cheburkin U.V., Galagudza M.M. Neurohumoral, cardiac and inflammatory markers in the evaluation of heart failure severity and progression. Journal of Geriatric Cardiology. 2021; 47-66. IF 2,418. Access link:—5411.2021.01.007


Heber Ivan Condori Leandro, Aleksandr D. Vakhrushev,  Natalia S. Goncharova,  Lev E. Korobchenko,  Elena G. Koshevaya,  Lubov B. Mitrofanova,  Elizaveta M. Andreeva,  Olga M. Moiseeva,  Dmitry S. Lebedev,  Evgeny N. Mikhaylov. Stimulation mapping of the pulmonary artery for denervation procedures: an experimental study. Journal of Cardiovascular Translational Research. 2020; 1-10 DOI:10.1007/s12265-020-10079-4. IF 3,28. Access link:

Vakhrushev A.D., Condori Leandro H.I., Goncharova N.S., Korobchenko L.E., Mitrofanova L.B., Lebedev D.S., Mikhaylov E.N… Extended Renal Artery Denervation Is Associated with Artery Wall Lesions and Acute Systemic and Pulmonary Hemodynamic Changes: A Sham-Controlled Experimental Study. Cardiovascular Therapeutics. 2020; 8859663 1-8 DOI:10.1155/2020/8859663. IF 2,51. Access link:

Mariniello M., Petruzzelli R., Wanderlingh L.G., La Montagna R., Carissimo A., Pane F., Amoresano A., Ilyechova E. Y., Galagudza M. M., Catalano F., Crispino R., Puchkova L. V., Medina D. L., Polishchuk R. S. Synthetic lethality screening identifies FDA-approved drugs that overcome ATP7B-mediated tolerance of tumor cells to cisplatin. Cancers (Basel). 2020;12 (3): ID 608 (эл.рес.). doi: 10.1007/s00441-019-03130-7. Access link:

Belostotskaya G., Hendrikx M., Galagudza M., Suchkov S. How to Stimulate Myocardial Regeneration in Adult Mammalian Heart: Existing Views and New Approaches. BioMed Research International. 2020;2020: ID 7874109 эл.рес.):1-9. DOI: 10.1155/2020/7874109. Access link:

Sonin D, Pochkaeva E, Zhuravskii S, Postnov V, Korolev D, Vasina L, Kostina D, Mukhametdinova D, Zelinskaya I, Skorik Y, Naumysheva E, Malashicheva A, Somov P, Istomina M, Rubanova N, Aleksandrov I, Vasyutina M, Galagudza M. Biological Safety and Biodistribution of Chitosan Nanoparticles. Nanomaterials (Basel). 2020; 10 (4): 810. Access link:

Polyakova E.A., Mikhaylov E.N… The prognostic role of high-sensitivity C-reactive protein in patients with acute myocardial infarction. Journal of Geriatric Cardiology. 2020; 17 (7): 379-383. IF 2,41. Access link:—5411.2020.07.007

Elena Y. Smirnova, Anton V. Chizhov,  Aleksey V. Zaitsev. Presynaptic GABAB receptors underlie the antiepileptic effect of lowfrequency electrical stimulation in the 4-aminopyridine model of epilepsy in brain slices of young rats. Brain Stimulation. 2020; 13: 1387—1395. IF 6,722. Access link:


Podolsky N. E., Marcos M. A., Cabaleiro D., Semenov K. N., Lugo L., Petrov A. V., Charykov N. A., Sharoyko V. V., Vlasov T. D., Murin I. V. Physico-chemical properties of C60 (OH) 22-24 water solutions: Density, viscosity, refraction index, isobaric heat capacity and antioxidant activity. Journal of Molecular Liquids. 2019;278:342-355. DOI: 10.1016/j.molliq.2018.12.148. Access link:

Borshchev, Y.Y., Uspensky, Y.P., Galagudza, M.M. Pathogenetic pathways of cognitive dysfunction and dementia in metabolic syndrome. Life Sciences. 2019; 237: ID 116932 (эл.рес.). DOI: 10.1016/j.lfs.2019.116932. Access link:

Borshchev, Y.Y., Minasian, S.M., Burovenko, I.Y., Borshchev, V.Y., Protsak, E.S., Semenova, N.Y., Borshcheva, O.V., Galagudza, M.M. Effects of tetracycline on myocardial infarct size in obese rats with chemically-induced colitis. PLoS ONE. 2019; 14 (11), ID e0225185 (эл. ресурс). DOI: 10.1371/journal.pone.0225185. Access link:

Baysa, A; Fedorov, A; Kondratov, K; Ruusalepp, A; Minasian, S; Galagudza, M; Popov, M; Kurapeev, D; Yakovlev, A; Valen, G; Kostareva, A; Vaage, J; Stenslokken, KO. Release of Mitochondrial and Nuclear DNA During On-Pump Heart Surgery: Kinetics and Relation to Extracellular Vesicles. JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH. 2019; 12 (3): 184-192. DOI: 10.1007/s12265-018-9848-3. Access link:

Agalakova N. I., Reznik V. A., Nadei O. V., Ershov I. A., Rassokha O. S., Vasyutina M. L., Ivanov D. O., Adair C. D., Galagudza M. M., Bagrov A. Y. Antibody against Na/K-ATPase Inhibitor Lowers Blood Pressure and Increases Vascular Fli1 in Experimental Preeclampsia // American Journal of Hypertension. 2019; ID hpz180 (эл.рес.):1-6. DOI: 10.1093/ajh/hpz180. Access link:

Smolyanskaya O. A., Lazareva E. N., Nalegaev S. S., Petrov N. V., Zaytsev K. I., Timoshina P. A., Tuchina D. K., Toropova Ya. G., Kornyushin O. V., Babenko A. Yu., Guillet J. -P., Tuchin V. V. Multimodal Optical Diagnostics of Glycated Biological Tissues. – Biochemistry (Moscow). 2019;84 (1):S124-S143. DOI: 10.1134/S0006297919140086. Access link:

Karpov A. A., Puzanov M. V., Ivkin D. Yu., Krasnova M. V., Anikin N. A., Docshin P. M., Moiseeva O. M., Galagudza M. M. Non-inferiority of microencapsulated mesenchymal stem cells to free cells in cardiac repair after myocardial infarction: A rationale for using paracrine factor (s) instead of cells. International Journal of Experimental Pathology. 2019;100 (2):102-113. DOI: 10.1111/iep.12312. Access link:

Korolev D. V., Evreinova N. V., Zakharova E. V., Gareev K. G., Naumysheva E. B., Postnov D. V., Postnov V. N., Galagudza M. M. Phosphocreatine immobilization of the surface of silica and magnetite nanoparticles for targeted drug delivery. Russian Chemical Bulletin. 2019;68 (5):1096—1101. DOI: 10.1007/s11172-019-2525-0. Access link:

Knyazeva, A; Krutikov, A; Golovkin, A; Mishanin, A; Pavlov, G; Smolina, N; Hushkina, A; Sejersen, T; Sjoberg, G; Galagudza, M; Kostareva, A. Time- and Ventricular-Specific Expression Profiles of Genes Encoding Z-Disk Proteins in Pressure Overload Model of Left Ventricular Hypertrophy. FRONTIERS IN GENETICS. 2019; 9: ID 684 (эл.ресурс). DOI: 10.3389/fgene.2018.00684. Access link:

Thirugnanam K, Cossette SM, Lu Q, Chowdhury SR, Harmann LM, Gupta A, Spearman AD, Sonin DL, Bordas M, Kumar SN, Pan AY, Simpson PM, Strande JL, Bishop E, Zou MH, Ramchandran R. Cardiomyocyte-Specific SNRK Prevents Inflammation in the Heart. J Am Heart Assoc. 2019; 8 (22): e012792. Access link:


Belostotskaya, G.B., Nerubatskaya, I.V., Galagudza, M.M. Two mechanisms of cardiac stem cell-mediated cardiomyogenesis in the adult mammalian heart include formation of colonies and cell-in-cell structures. 2018; 9 (75):34159-34175. DOI: 10.3389/fncel.2017.00264. Access link:

Filchenko I., Simanenkova A., Chefu S., Kolpakova M., Vlasov T. Neuroprotective effect of glucagon-like peptide-I receptor agonist is independent of glycaemia normalization in type two diabetic rats. Diabetes and Vascular Disease Research. 2018;15 (6):567-570. DOI: 10.1177/1479164118788079. Access link:

Papayan G., Akopov A. Potential of indocyanine green near-infrared fluorescence imaging in experimental and clinical practice. Photodiagnosis and Photodynamic Therapy. 2018;24:292-299. DOI: 10.1016/j.pdpdt.2018.10.011. Access link:

Zykov V. A., Tuchina T. P., Lebedev D. A., Krylova I. B., Babenko A. Y., Kuleshova E. V., Grineva E. N., Bayramov A. A., Galagudza M. M. Effects of glucagon-like peptide 1 analogs in combination with insulin on myocardial infarct size in rats with type 2 diabetes mellitus. World Journal of Diabetes. 2018;9 (9):149-156. Access link:

Toropova Ya. G., Pechnikova N. A., Zelinskaya I. A., Zhuravsky S. G., Kornyushin O. V., Gonchar A. I., Ivkin D. Yu., Leonova Yu. V., Karev V. E., Karabak I. A. Nicotinamide riboside has protective effects in a rat model of mesenteric ischaemia-reperfusion. International Journal of Experimental Pathology. 2018;99 (6):304-311. DOI: 10.1111/iep.12302. Access link:

Zykov V. A., Tuchina T. P., Lebedev D. A., Krylova I. B., Babenko A. Y., Kuleshova E. V., Grineva E. N., Bayramov A. A., Galagudza M. M. Effects of glucagon-like peptide 1 analogs in combination with insulin on myocardial infarct size in rats with type 2 diabetes mellitus. World Journal of Diabetes. 2018;9 (9):149-156. Access link:

Docshin P. M., Karpov A. A., Eyvazova Sh. D., Puzanov M. V., Kostareva A. A., Galagudza M. M., Malashicheva A. B. Activation of Cardiac Stem Cells in Myocardial Infarction. Cell and Tissue Biology. 2018;12 (3):175-182. Access link:,from%20a%20healthy%20myocardial%20area.&text=We%20conclude%20that%20myocardial%20ischemia,potential%20of%20cardiac%20stem%20cells.

Berezovskaya G., Smirnova O., Malev E., Khromov-Borisov N., Klokova E., Karpenko M., Papayan L., Petrishchev N. Thrombin generation test for evaluation of antiplatelet treatment in patients with coronary artery disease after percutaneous coronary intervention. Platelets. 2018; 29 (2):185-191. DOI: 10.1080/09537104.2017.1294680. Access link:


D. Sonin, G. Papayan, E. Pochkaeva, S. Chefu, S. Minasian, D. Kurapeev, J. Vaage, N. Petrishchev, and М.lGalagudza.In vivo visualization and ex vivo quantification of experimental myocardial infarction by indocyanine green fluorescence imaging.Biomedical Optics Expres. Vol. 8, Issue 1,p. 151-161. 2017


Galagudza M., Sonin D., Vlasov T., Kurapeev D., Shlyakhto E. Remote versus local ischemic preconditioning in the rat heart: infarctlimitation, suppression of ischemic arrhythmia, and the role of reactive oxygen species // European Heart Journal Supplements. – 2016. – V.97. –№ 1. – Р 66-74.


Sonin D. L., Korolev D. V., Postnov V. N., Naumysheva E. B., Pochkaeva E. I., Vasyutina M. L., Galagudza M. M. Silicon-containing nanocarriers for targeted drug delivery: synthesis, physicochemical properties and acute toxicity // Drug Delivery. – 2015. – Published online: 23 Jul 2015. – P. 1-10. – doi: 10.3109/10717544.2015.1069421.

KangUk, PapayanG,V., ObuckhovaN.F., BaeS.J., LeeD.S., JungM.W., BerezinV/B. MotikoF.F., PlochichD.G., SljbodeniukC.f. Complex for fluorescent diagnostics and photodynamic therapy of cervical disease. J. Opt. Technol. N12. 47-59. 2015.

A.Kondratyev, A.Lyaptsev, I.Mikhailova.Mathematical Modeling of Thrombus Growth. Phenomenological Models. Applied Mathematical Sciences.V.9 .N 9.p.429-446 . 2015.

Petrishchev N.N. Papayan G.V. GryshachovaT.G ., Mikhailova I.A…Struy A.V. Photoreactivity of microvessels of rat mesenteric vascular bed/ J.Vasc.Res, V.52 (Suppl 1). p.14. 2015.

Patents and certificates

Patent No. 2456024 issued on 20.07.2012, application No. 2010116541 dated 26.04.2010
“Method of cardiac protection”
Authors: Galagudza M., Korolev D., Syrensky A., Sonin D., Aleksandrov I., Minasyan S., Postnov V., Kirpicheva E.

Patent No. 2622983 issued on 21.06.2017, application No. 2016130494 dated 25.07.2016
«Method for intraoperative imaging of myocardial ischemia-reperfusion injury»
Authors: Papayan G., Petrischev N., Galagudza M., Sonin D., Minasyan S.

Patent for invention No. 2675353 registered on 18.12.2018, application No. 2018119575 dated 28.05.2018
“A method for modeling chronic thromboembolic pulmonary hypertension”
Authors: Karpov A., Lomakina A., Cherepanov D., Anikin N., Krasnova M., Ivkin D., Galagudza M.

Computer program No. 2018665061 registered on 29.11.2018, application No. 2018661604 dated 22.10.2018
«Software for digital processing of histological images of the necrotic zones (black shadow)»
Authors: Borshchev V., Burovenko I., Borshchev Yu., Galagudza M., Korolev D.

Patent for invention No. 2707377 registered on 26.11.2019, application No. 2019107869 dated 19.03.2019
«Method for intraoperative imaging of machine stitch failure in sleeve gastrectomy»
Authors: Kovalev A., Kornyushin O., Papayan G., Masley V., Bulavinova N., Neimark A., Danilov I., Voronin S.

Patent for invention No. 2694509 registered on 15.07.2019, application No. 2018132156 dated 07.09.2018
«Hydrodynamic stand for testing of the vascular wall permeability for magnetic nanoparticles using an external magnetic field»
Authors: Mishanin V., Istomina M., Korolev D., Kornyushin O., Toropova Ya.

Patent for invention No. 2722454 registered on 01.06.2020, application No. 2019140321 dated 06.12.2019
«Method for determining the risk of repeated myocardial revascularization in patients with coronary artery disease after percutaneous coronary intervention with stenting»
Authors: Polyakova E., Biryukov A., Berkovich O., Baranova E., Shlyakhto E.

Patent for invention No. 2716596 registered on 13.03.2020, application No. 2019128217 dated 06.09.2019
«Method for reducing the size of myocardial ischemia-reperfusion injury using quinacrine»
Authors: Polyakova E., Biryukov A., Berkovich O., Baranova E., Shlyakhto E.

Patent for invention No. 2749477 registered on 11.06.2021, application No. 2020113871 dated 03.04.2020
«Method for modeling male hypogonadotropic hypogonadism»
Authors: Bayramov A., Nikitina I., Yukhlina Yu., Grineva E., Shabanov P., Galagudza M., Kelmanson I., Masel A., Zelener A., Sarakaeva L., Plaksina A.

Patent for invention No. 2746435 registered on 14.04.2021, application No. 2020113872 dated 03.04.2020
«Method for modeling an infected wound in SPF rats»
Authors: Galagudza M., Toropova Ya., Belsky Yu., Belskaya N.

Patent for invention No. 2750713 registered on 01.07.2021, application No. 2020134504 dated 20.10.2020
«Method for treating adolescent hypogonadotropic hypogonadism in the experiment»
Authors: Nikitina I., Bayramov A., Yukhlina Yu., Shabanov P., Galagudza M., Grineva E., Droblenkov A., Masel A., Zelener A., Sarakaeva L., Plaksina A.

Dmitry Sonin, Leading Researcher, Head of Department


Уведомляем вас, что в соответствии с Федеральным законом от 06.03.2006 № 35-ФЗ «О противодействии терроризму» в Центре Алмазова введен комплекс дополнительных мер по безопасности, направленный на предотвращение террористических актов. В целях обеспечения безопасности граждан и целостности объектов инфраструктуры при посещении Центра Алмазова проводится дополнительный личный осмотр, осмотр вещей и автотранспорта. Отказ от соблюдения мер по безопасности может послужить причиной недопуска на территорию Центра Алмазова. Просим с пониманием отнестись к введенным мерам по безопасности.

С уважением, Администрация Центра Алмазова