Reserch into Practice

 

Making CAR-T cell therapy accessible in Russia

Modern medicine is increasingly using the achievements of biotechnology and cell biology to achieve not only longer life expectancy, but also a better quality of life. However, there is a long way to go from the success of fundamental science, in particular, experimental oncology and oncoimmunology, to clinical practice. Many Russian families faced with a terrible diagnosis of cancer refuse to perceive it as a death sentence and are looking for accessible research advancements, modern high-quality care and treatment.
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New-generation artificial heart implanted for the first time at Almazov Centre

The surgeons of Almazov Centre performed a rare surgery in a young man to implant a new-generation domestic ventricular assist device designed for long-term mechanical support of the left ventricle.

A 35-year-old man from Kaliningrad was admitted to Almazov Centre in October 2018 with decompensated chronic heart failure on the background of dilated cardiomyopathy – the impaired contractile function of the heart muscle (myocardium) with marked dilatation of heart chambers. According to statistics, only 30% of patients with this disease survive the first five years…

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ITMO University and Almazov Centre scientists have developed a new non-contact method of measuring blood flow in arms

A research team from ITMO University and Almazov Centre proposed a new non-contact method for measuring blood flow in the upper limbs. The method is based on video recording of the skin surface under green light measuring the absorption of red blood cells. This helps see how effective the circulatory system and the blood flow regulation are. The experimental results showed that the proposed method is as accurate as the traditional one. However, it is easier to use, cheaper and suitable for more patients. The research was published in Biomedical Optics Express.

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Innovative treatment of lower limb varicose vein disease

Lower limb varicose vein disease is a major problem in healthcare worldwide. About 25% of the Russian population suffers from various forms of varicose vein disease, and its prevalence and frequency continue to grow. Having a progressive irreversible course, the disease leads to various manifestations of chronic venous insufficiency, including non-healing venous ulcers and venous thromboembolism. In order to prevent the development of such serious complications, patients are encouraged to start treatment as soon as possible.
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Biobank: the link between donors, science and clinical practice

Today, one of priorities for Almazov Centre is the work on personalized and translational medicine in the Centre, in St. Petersburg and in Russia. Translational medicine is a fast transfer of basic research results (mainly in the field of cell and molecular biology and biochemistry) into clinical practice, i.e. the creation of diagnostic protocol or therapeutic treatment target based on the identified molecular-cellular mechanisms of disease pathogenesis. The aim of personalized medicine is to create diagnostic algorithms and treatment strategy taking into account patient’s individual (genetic) characteristics. Today, these types of clinical practice include molecular diagnostics and pharmacogenetics.

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