Somnology Group

 
Yury Sviryaev, MD, DSc
Head of Group

Somnology Group was established in 2013 as a separate division of the Research Department for Arterial Hypertension of the Heart and Vessels Institute. The specialists of the Research Department for Arterial Hypertension have been diagnosing and consulting patients for sleep disorders since 2002.

The specialists of the Laboratory have been trained in Moscow (Centre for Sleep Medicine, Federal Research Clinical Centre) and European laboratories (Marie Curie project “Training in Sleep Research”), have been certified by ESRS (“Somnologist – Expert in Sleep Medicine” certificates) and are members of the cardiology society and American Academy of Sleep Medicine (AASM).

Areas of focus

  • Research

Clinical research focuses on sleep disorders and their association with cardiovascular disease, their prognostic role and prevention approaches. As a result of research, 3 candidate and one doctoral theses were defended. The ongoing research includes the study of CPAP/BiPAP therapy for heart rhythm and conduction disorders. As part of the international project “Seventh Framework Programme” patients with heart failure are examined and followed-up in sleep laboratory. Also, our specialists initiated a project for the assessment of sleep disorders in patients before and after heart transplantation. Together with the pediatricians of the Centre, we investigate the association between sleep quality, metabolic disorders, neurocognitive performance, emotional and behavioral characteristics in children.

Jointly with the Research Laboratory for Epidemiology of Hypertension, we conduct screenings for the St. Petersburg population as part of the large-scale epidemiological studies to assess cardiovascular disease in different regions of Russia.

  • Clinical practice

The specialists of the Laboratory provide both outpatient and inpatient consultations at Almazov Centre. All types of diagnostic devices (according to the AASM classification) are available to perform the following sleep tests: attended in-lab full video-polysomnography; unattended polysomnography in cardiology wards; cardiorespiratory monitoring (with a simultaneous 12-channel ECG monitoring) and night pulse oximetry with a simultaneous oronasal airflow recording. The last 2 types are screening tests and are used for as primary diagnostic tools only. Actigraphy is used for the evaluation of circadian rhythm disorders. The laboratory can also select the treatment for sleep-related breathing disorders, primarily various modes of PAP (positive airway pressure) therapy, which is the treatment of choice for sleep apnea. If necessary, complex treatment using an oxygen concentrator is used. Patients receiving PAP therapy are followed up to assess the effect of therapy on the main clinical and laboratory parameters. In addition to the diagnosis and treatment of sleep-related breathing disorders, somnology specialists focus on the detection, assessment and treatment of circadian rhythm sleep-wake disorders, and provide comprehensive diagnosis for patients with insomnia and other sleep disorders.

The specialists of the Perinatal Centre provide diagnosis and treatment of sleep disorders in children.

  • Training and education

The specialists of the Somnology Group give lectures at the advanced training courses for cardiologists and specialists in functional diagnostics on the management of sleep disorders (courses “Innovative Technologies for the Treatment of Arterial Hypertension”, etc.), take part in the project of continuous medical education.

Grant-supported projects

Russian Fundamental Research Foundation, #15-07-02472 А: The development of the algorithm for the non-contact evaluation of sleep in humans, based on bioradiolocation monitoring, 2015–2017. Project “The development of a portable device for multifunctional cardiovascular monitoring and sleep-wake cycle assessment”, State Grant for Young Russian Scientists, 2015. Russian Humanitarian Scientific Foundation #14-06-00219: Theoretical and experimental study of the screening surveys of sleep quality for prevention and preclinical management of socially significant diseases, 2014—2016. Russian Fundamental Research Foundation, #14-07-31151, young investigators: Development of the Algorithms for Sleep Architecture Detection Based on the Cardiorespiratory Variability, 2014—2015. Russian Fundamental Research Foundation, #14-07-00019A: Theoretical and Experimental Study for the Development of Algorithm for Spectral Heart Rhythm Variability Analysis in Human Short ECG Recordings, 2014. Grant of St. Petersburg Administration for students, postgraduate students, young scientists and young PhDs for 2013, diploma PSP #13218, project “Prognostic role of obstructive sleep apnea syndrome for the development of glucose metabolism disorders”.

Russian Fundamental Research Foundation, #12-07-31014: Research and Development of Methods and Algorithms for Nonstationary Bio-radiolocation Signals Pattern Recognition for Non-Contact Screening Diagnostics of Sleep-disordered Breathing, 2012.

Collaboration

Our specialists collaborate with colleagues from Almazov Centre (neurologists, endocrinologists, ENT-doctors, psychologists and psychotherapists) as well as with other leading institutions of St. Petersburg (Sechenov Institute of Evolutionary Physiology and Biochemistry, First Pavlov State Medical University, Herzen State Pedagogical University of Russia, City Clinical Hospital No. 2, St. Petersburg Clinical Hospital of Russian Academy of Sciences and others). It allows for an integrated approach to the diagnosis and treatment of various sleep disorders.

Together with INKART company, the diagnostic algorithms for sleep disorders are being studied and enhanced for further development of the portable system for multifunctional cardiovascular evaluation in the sleep-wake cycle.

Events

In 2014 and 2015, together with somnologists from Moscow, our specialists organized different activities for the World Sleep Day and received the Distinguished Activity Award of the World Association of Sleep Medicine. The specialists of the Somnology Group take an active part in different social events for the prevention and treatment of sleep disorders promoting healthy sleep. They give lectures for people with cardiovascular, endocrine and other diseases, give interviews on TV, radio and other media and publish articles on the role of sleep.

The 13th Youth Somnology Training Workshop was held at Almazov Centre in St. Petersburg on May 14-16, 2015 (as part of the Korotkov Congress).

Major publications

Dmitrieva R. I., Revittser A. V., Klukina M. A., Sviryaev Y. V., Korostovtseva L. S., Kostareva A. A., Zaritskey A. Y., Shlyakhto E. V. Functional properties of bone marrow derived multipotent mesenchymal stromal cells are altered in heart failure patients, and could be corrected by adjustment of expansion strategies. Aging (Albany NY). 2015 Jan 9. [Epub ahead of print]

Minullina I. R., Alexeyeva N. P., Anisimov S. V., Puzanov M. V., Kozlova S. N., Sviryaev Y. V., Zaritskey A. Y., Shlyakhto E. V. Transcriptional changes in bone marrow stromal cells of patients with heart failure. Cell Cycle. 2014. Т. 13. № 9. С. 1495—1500.

Tataraidze A.,Anishchenko L., Alekhin M., Korostovtseva L., Sviryaev Y. Estimation of respiratory rhythm during night sleep using a bio-radar. Proceedings of SPIE — The International Society for Optical Engineering. 2014.  Vol. 9077.  90770Z-6.

Korostovtseva L. S., Sviryaev Yu. V., Zvartau N. E., Drugkova T., Tihonenko V. M., Konradi A. O. New insights into the management of rhythm and conduction disorders after acute myocardial infarction. American Journal of Case Reports. 2014. Vol. 15. P. 1-4. doi: 10.12659/AJCR.890357

Alekhin M., Anishchenko L., Tataraidze A, Ivashov S., Parashin V., Korostovtseva L., Sviryaev Y., Bogomolov A. A Novel Method for Recognition of Bioradiolocation Signal Breathing Patterns for Noncontact Screening of Sleep Apnea Syndrome. International Journal of Antennas and Propagation. Volume 2013 (2013), Article ID: 969603, 8 pages.

Alekhin M. D., Anishchenko L. N., Tataraidze A. B., Ivashov S. I., Korostovtseva L. S., Sviryaev Y. V., Bogomolov A. V. Selection of wavelet transform and neural network parameters for classification of breathing patterns of bio-radiolocation signals. communications in computer and information science. Proceedings of the First International Aizu Conference on Biomedical Informatics and Technology (ACBIT 2013). Springer, Heidelberg. 2013. Vol. 404. P. 327-330.

Alekhin M.D., Anishchenko L.N., Zhuravlev A.V., Ivashov S.I., Korostovtseva L.S., Sviryaev Y.V., Konradi A.O., Parashin V.B., Bogomolov A.V. Estimation of Information Value of Diagnostic Data Obtained by Bioradiolocation Pneumography in Non-contact Screening of Sleep Apnea Syndrome. Biomedical Engineering. 2013. Vol. 47, Issue 2. P. 96-99.

Rotar O. P., Trifonova E. A., Korostovtseva L. S., Erina A. A., Boiarinova M. A., Kolesova E. P., Dudorova E. A., Alekhin A. N., Konradi А. О., Tanicheva A.A. Health behaviours and attitudes in young and middle-aged Saint-Petersburg citizens (Russia). J Addiction Res. Ther. 2012. S8.

Konradi A. O., Rotar O. P., Korostovtseva L. S., Ivanenko V. V., Solntcev V. N., Anokhin S. B., Bart V. A., Shlyakhto E. V. Prevalence of metabolic syndrome components in a population of bank employees from St. Petersburg, Russia. Metab Syndr Relat Disord. 2011. Vol. 9, №5. 337-43.

Korostovtseva L. S., Sviryaev Y. V., Zvartau N. E., Konradi A. O., Kalinkin A. L. prognosis and cardiovascular morbidity and mortality in prospective study of hypertensive patients with obstructive sleep apnea syndrome in St Petersburg, Russia. Medical Science Monitor. 2011. Vol. 17. № 3. p. 8.