Director General of Almazov National Medical Research Centre

 
Evgeny Vladimirovich Shlyakhto

Evgeny Vladimirovich Shlyakhto

Evgeny Shlyakhto, Director General of Almazov National Medical Research Centre, Academician of the Russian Academy of Science, President of the Russian Society of Cardiology, chief visiting cardiologist of the Russian Ministry of Health for the Volga, Southern, North Caucasian and Northwestern federal districts, chief visiting cardiologist of St. Petersburg Health Committee, Honoured Scientist of Russia, Honorary Citizen of Saint Petersburg…

Major research interests: development and implementation of new methods for the diagnosis and treatment of CVDs, solving theoretical and practical problems of organizing the specialized and high-tech medical care, research in translational medicine, molecular diagnostics, diagnostic tools for personalized therapy, cellular and tissue engineering for therapeutic purposes, biocompatible materials and tissue-engineered constructs designed to provide high-tech care to patients with cardiovascular, endocrine and blood diseases. Creation and support of a Russia’s largest medical research and educational facility of a new type ensuring coordinated scientific research and high-quality training for the rapid implementation of results into practice and the training of qualified specialists based on the concept of translational medicine.

Education and specialization

1977 – graduated from the Pavlov First Saint Petersburg State Medical University.

1991 – defended his DSc thesis in Cardiology on the topic “Neurogenic mechanisms involved in the pathogenesis of hypertension and their role in the hypotensive effect of some antihypertensive drugs.”

1994 – received the Professor title.

1994–2001 – Vice Rector for Research at the Pavlov First Saint Petersburg State Medical University.

1997 – till now – Head of the Faculty Therapy Chair at the University.

2001 – Director of the Research Institute of Cardiology (later known as Almazov Research Institute of Cardiology, Almazov Federal Heart, Blood and Endocrinology Centre, Almazov Federal Medical Research Centre, Almazov North-West Federal Medical Research Centre, currently – Almazov National Medical Research Centre).

Since 2001 – Chief Cardiologist of Saint Petersburg, since 2002 — chief visiting cardiologist of the Russian Ministry of Health for the Northwestern federal district, since 2018 — chief visiting cardiologist of the Russian Ministry of Health for the Volga, Southern, North Caucasian and Northwestern federal districts.

Since 2004 – Honoured Scientist of Russia for contribution to the development of priority areas.

2010 – became a member of the WHO Expert Working Group.

Since 2011 – President of the Russian Society of Cardiology.

2014 – received the title of Academician of the Russian Academy of Sciences for scientific results in research in the field of pathophysiology of the cardiovascular system.

In April 2020, Evgeny Shlyakhto was appointed the head of the Interdepartmental Medical Working Group at the Interdepartmental Council on the prevention of the spread of the new coronavirus infection (COVID-19) in St. Petersburg targeting on the most relevant issues of organizing medical care for patients in all areas together with the expert community, St. Petersburg Health Committee, Federal Service for Surveillance in Healthcare (Roszdravnadzor) and Federal Service for the Oversight of Consumer Protection and Welfare (Rospotrebnadzor).

On April 27, 2020 Evgeny Shlyakhto was appointed Healthcare Advisor to the Governor of St. Petersburg.

In May 2020, Evgeny Shlyakhto was declared Honorary Citizen of St. Petersburg by the decision of the St. Petersburg Legislative Assembly. The Honorary Citizen title is the highest recognition of an outstanding contribution to the development of St. Petersburg, increasing its importance and authority in Russia and globally, strengthening democracy and protecting human rights, as well as in science, art, spiritual and moral development of the society.

Membership in national and international societies

Honorary Member of the European Society of Cardiology.
Honorary Member of the American Heart Association.
Honorary Member of the American College of Cardiology.
Member of the ESC Congress Programme Committee.
Member of the ESC Committee for Practice Guidelines.
Member of the Presidium of the Russian Academy of Sciences.
Member of the Presidential Council for Science and Education.
Member of the Presidential Council for Grants for the State Support of Young Russian Scientists and Leading Scientific Schools of the Russian Federation.
Member of the Council for Regional Healthcare under the Federation Council of the Federal Assembly of the Russian Federation.
Member of the Expert Council on Health Care under the Federation Council Committee on Social Policy.
Deputy Chairman of the Scientific Council of the Russian Ministry of Health.
Vice President of the National Medical Chamber.
President of the Russian Society of Cardiology.
Member of the Medical Council under the Governor of St. Petersburg.
Member of the Scientific and Technical Council of the St. Petersburg Government.
Member of the Interdepartmental NW Coordinating Board of RAS on Basic and Applied Research.
Chair of the Central Certification Commission for the Northwestern federal district.
Member of the Public Council under the Russian Ministry of Internal Affairs for Saint Petersburg and Leningrad region.
Co-chair of the Health Working Group for the Russian-German Forum Petersburg Dialog.

Membership in editorial boards

Editor-in-Chief of medical journals: Russian Journal of Cardiology, Translational Medicine and Journal of Arrhythmology.

Member of the editorial board of the European Heart Journal.

Е. В. Шляхто — инициатор проведения в Санкт-Петербурге ряда крупнейших кардиологических форумов

Evgeny Shlyakhto is an initiator of major cardiology forums in Saint Petersburg

State Assignment

Almazov Centre implements the state assignment on more than 50 topics in priority areas “Cardiology and Angiology”, “Invasive Technologies”, “Neurology and Neurosciences”, “Oncology”, “Pediatrics”, “Endocrinology”, “Pharmacology”, “Microbiology”, “Reproductive Health”. Prof. Evgeny Shlyakhto acts as direct supervisor for assignments performed on the following topics:

  • Study of the autonomic regulation of blood circulation and development of diagnostic and treatment methods for cardiovascular diseases based on the impact on the autonomic nervous system.
    Project objective: to develop methods for diagnosing autonomic dysfunction and treatment methods for cardiovascular diseases based on physical and pharmacological effects on nerves and ganglionated plexi.
  • Risk stratification, routing, selection of the optimal treatment strategy and early prediction of outcomes in patients with cardiac emergencies based on decision support systems.
    Project objective: to develop personalized approaches to risk stratification, routing and early prediction of outcomes in patients with cardiac emergencies in order to choose the optimal treatment strategy and improve early and long-term outcomes.

Training and education

Evgeny Shlyakhto is an acknowledged academic authority contributing into academic activities. He is the founder of a scientific school known in Russia and abroad for tradition continuity and interdisciplinary approach to integrated solution of current scientific problems based on breakthrough technologies. Twenty doctorate and fifty-seven PhD theses were defended under his guidance and scientific advice.

In 2008, Almazov Centre acquired the status of ESH Hypertension Excellence Centre. In 2013, the Medical Education Institute was established; currently it has 3 faculties and 22 departments offering the programmes of basic and additional professional education.

Personal achievements

2009 — Russian Federation Government Prize in science and technology for the implementation of a set of activities to create and implement in Russia the modern methods of diagnosis, treatment and rehabilitation of patients with chronic heart failure of various etiologies.

2011— Prize for scientific and technological achievement in Physiology and Medicine from the Saint Petersburg Government and St. Petersburg Scientific Centre of the Russian Academy of Sciences.

2012 — Order of Merit for the development of healthcare and medical science in the Russian Federation.

2013 — Burakovsky Medal for the development and introduction of new medical technologies.

2014 — Award of the St. Petersburg Government for outstanding achievements in higher and secondary education for “Scientific achievements improving the quality of training and highly qualified personnel” and “Development and implementation of continuous postgraduate medical education based on the translational medicine concept”.

2014 — Certificate of Appreciation of the St. Petersburg Legislative Assembly for exceptional personal contribution to healthcare in St. Petersburg.

2014 — Certificate of Appreciation from the St. Petersburg Governor for longstanding and fruitful work and substantial contribution to healthcare development in Saint Petersburg.

2014 — Certificate of Merit of the St. Petersburg Health Committee for contribution to healthcare development in Saint Petersburg.

2014 — Certificate of Merit of the St. Petersburg Committee on Science and Higher Education for contribution to the development of research potential of St. Petersburg.

2017 — Order of Merit for Country of the IV Degree for the development of healthcare and medical science in the Russian Federation.

2018 — ESC Gold Medal of the European Society of Cardiology for contribution to the development of healthcare and medical science in the Russian Federation.

2019 — Award for Merit to Saint Petersburg for contribution to the development of healthcare and medical science in Saint Petersburg.

2020 — Healthcare Advisor to the Governor of St. Petersburg.

2020 — Honorary Citizen of St. Petersburg declared by the decision of the St. Petersburg Legislative Assembly for an outstanding contribution to the development of St. Petersburg, increasing its importance and authority in Russia and globally.

H-index (RSCI) – 54, h-index (Scopus) – 29, h-index (WOS) – 23.
Publication in RSCI – 965, publications in Scopus – 306, publications in WOS – 420.
Monographs (chapters) – 58, patents – 24, discoveries – 2.
ORCID ID: 0000—0003—2929-0980, WOS Researcher ID: A-6939—2014, Scopus Author ID: 16317213100.

Selected publications

2020 

Konstantinides S.V., Meyer G., Becattini C., Bueno H., Geersing G.Ja., Harjola V.P., Huisman M.V., Humbert M., Jennings C.S., Jiménez D., Kucher N., Lang I.M., Lankeit M., Lorusso R., Mazzolai L., Meneveau N., Ní Áinle F., Prandoni P., Pruszczyk P., Righini M., Shlyakhto E.V. et al. 2019 ESC guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the european respiratory society (ERS). EUROPEAN HEART JOURNAL. 2020;41 (4):543-603. IF 22,70. Access link: https://pubmed.ncbi.nlm.nih.gov/31504429/.

Cosentino F, Grant PJ, Aboyans V, et al. 2019 ESC guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. European Heart Journal. 2020;41 (2):255-323. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/41/2/255/5556890.

Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European respiratory society (ERS). European Heart Journal. 2020;41 (4):543-603. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/41/4/543/5556136.

Mikhaylov EN, Moshonkina TR, Zharova EN, et al. Аcute cardiovascular effects of non-invasive electrical spinal cord stimulation: results from a pilot study in humans. J Cardiovasc Transl Res. 2020 May 6. IF 2,319. Access link: https://link.springer.com/article/10.1007%2Fs12265-020-10014-7.

2019 

Neumann FJ, Byrne RA, Falk V, et al. 2018 ESC/EACTS guidelines on myocardial revascularization. European Heart Journal. 2019;40 (2):87-165. IF 24,889. Access link: https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/ESC-EACTS-Guidelines-in-Myocardial-Revascularisation-Guidelines-for.

Aquila G, Ferrari R, Kostina AS, et al. The notch pathway: a novel therapeutic target for cardiovascular diseases? Expert Opinion on Therapeutic Targets. 2019;23 (8):695-710. IF 4,621. Access link: https://pubmed.ncbi.nlm.nih.gov/31304807/.

Mach F, Baigent C, Catapano AL, et al. 2019 ESC/EAS guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Atherosclerosis. 2019;290:140-205. IF 4,225. Access link: https://academic.oup.com/eurheartj/article/41/1/111/5556353.

Sousa-Uva M, Neumann FJ, Ahlsson A, et al. 2018 ESC/EACTS guidelines on myocardial revascularization. European Journal of Cardio-Thoracic Surgery. 2019;55 (1):4-90. IF 3,486. Access link: https://academic.oup.com/ejcts/article/55/¼/5079878.

Barantsevich NE, Shlyakhto EV, Churkina IV, et al. Emergence of candida Auris in Russia. Journal of Hospital Infection. 2019;102 (4):445-448. IF 3,441. Access link: https://www.researchgate.net/publication/331582181_Emergence_of_Candida_auris_in_Russia.

Rotar O, Konradi A, Shlyakhto E. May measurement month 2017 in Russia: hypertension treatment and control – Europe. European Heart Journal Supplements. 2019; 21 (Suppl D): D101–D103. IF 1,655. Access link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480026/.

Babenko AY, Mosikian AA, Lebedev DL, et al. Mental state, psychoemotional status, quality of life and treatment compliance in patients with type 2 diabetes mellitus. Journal of Comparative Effectiveness Research. 2019;8 (2):113-120. IF 1,468. Access link: https://www.researchgate.net/publication/329667288_Mental_state_psychoemotional_status_quality_of_life_and_treatment_compliance_in_patients_with_Type_2_diabetes_mellitus.

Alfonso F, Zelveian P, Monsuez JJa, et al. Авторство: от авторского права до ответственности. Российский кардиологический журнал. 2019;24 (1):113-119. IF 1,305. Access link: https://cyberleninka.ru/article/n/avtorstvo-ot-avtorskogo-prava-do-otvetstvennosti.

Shalnova SA, Maksimov SA, Balanova YuA, et al. Alcohol consumption and dependence on sociodemographic factors in able-bodied people (according to the ESSE-RF study). Профилактическая медицина. 2019;22 (5):45-53. IF 1,066. Access link: https://www.mediasphera.ru/issues/profilakticheskaya-meditsina/2019/5/1230549482019051045.

Babenko AYu, Savitskaya DA, Kononova YuA, et al. Predictors of effectiveness of glucagon-like PEPTIDE-1 receptor agonist therapy in patients with type 2 diabetes and obesity. Journal of Diabetes Research. 2019;2019:1365162. IF 0,988. Access link: https://www.hindawi.com/journals/jdr/2019/1365162/.

2018 

Ibanez B, James S, Bueno H, et al. 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. European Heart Journal. 2018;39 (2):119-177. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/39/2/119/4095042.

Valgimigli M, Bueno H, Byrne RA, et al. 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS. European Heart Journal. 2018;39 (3):213-254. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/39/3/213/4095043.

Williams B, Dominiczak A, Lip GYH, et al. 2018 ESC/ESH guidelines for the management of arterial hypertension. European Heart Journal. 2018;39 (33):3021–3104. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/39/33/3021/5079119.

Regitz-Zagrosek V, Bauersachs J, Kintscher U, et al. 2018 ESC guidelines for the management of cardiovascular diseases during pregnancy. European Heart Journal. 2018;39 (34):3165–3241. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/39/34/3165/5078465.

Shlyakhto E. A new research centre in Russia. European Heart Journal. 2018;39 (4):271-272. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/39/4/271/4817821.

Shlyakhto E. A new paediatric centre in Russia. European Heart Journal. 2018;39 (4):273-274. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/39/4/273/4817822.

Aboyans V, Ricco JB, Bartelink MLEL, et al. 2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European society for vascular surgery (ESVS). European Heart Journal. 2018;39 (9):763-816. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/39/9/763/4095038.

Trukshina MA, Lyasnikova EA, Galenko V, et al. Clinical experience of using cardiac contractility modulation devices in patients with heart failure: the true or wrong way to success? European Journal of Heart Failure Supplements. 2018;20 (S1):265. IF 11,627. Access link: https://www.researchgate.net/publication/326985254_Clinical_experience_of_using_cardiac_contractility_modulation_devices_in_patients_with_heart_failure_the_true_or_wrong_way_to_success.

Williams B, Mancia G, Spiering W, et al. 2018 ESC/ESH guidelines for the management of arterial hypertension. Journal of Hypertension. 2018;36 (10):1956–2041. IF 4,171. Access link: https://www.researchgate.net/publication/327990610_2018_ESCESH_Guidelines_for_the_management_of_arterial_hypertension_The_Task_Force_for_the_management_of_arterial_hypertension_of_the_European_Society_of_Cardiology_and_the_European_Society_of_Hyperten.

Williams B, Mancia G, Spiering W, et al. 2018 practice guidelines for the management of arterial hypertension of the European society of cardiology and the European society of hypertension ESC/ESH task force for the management of arterial hypertension. Journal of Hypertension. 2018;36 (12):2284–2309. IF 4,171. Access link: https://journals.lww.com/jhypertension/Citation/2018/12000/2018_Practice_Guidelines_for_the_management_of.2.aspx.

Olmastroni E, Tragni E, Casula M, et al. Epidemiology of cardiovascular risk factors in two population-based studies. Atherosclerosis, Supplements. 2018;35:e14-e20. IF 3,968. Access link: https://pubmed.ncbi.nlm.nih.gov/30177370/.

Alieva AS, Rotar OP, Orlov AV, et al. Large artery stiffness according to different assessment methods in adult population of St. Petersburg. Atherosclerosis, Supplements. 2018;35:e1-e5. IF 3,968. Access link: https://www.sciencedirect.com/science/article/pii/S1567568818305518.

Zheleznova E, Zhernakova Y, Oshchepkova E, et al. Prevalence of abdominal obesity in russian federation and its relationship with arterial hypertention and others comorbidites. By the data of epidemiological study ESSE-RF. Journal of Hypertension, Supplement. 2018;36 (e-S1):e86. IF 2,88. Access link: https://journals.lww.com/jhypertension/Abstract/2018/06001/PREVALENCE_OF_ABDOMINAL_OBESITY_IN_RUSSIAN.261.aspx.

Shlyakhto E. Gendered innovations in the study of cardiovascular diseases. Advances in Experimental Medicine and Biology. 2018;1065:655-675. IF 2,45. Access link: https://www.researchgate.net/publication/326642562_Gendered_Innovations_in_the_Study_of_Cardiovascular_Diseases.

Williams B, Mancia G, Spiering W, et al. 2018 practice guidelines for the management of arterial hypertension of the European society of hypertension (ESH) and the European society of cardiology (ESC). Blood Pressure. 2018;27 (6):314-340. IF 2,169. Access link: https://www.tandfonline.com/doi/full/10.1080/08037051.2018.1527177.

Rotar OP, Boyarinova MA, Moguchaia EV, et al. Subclinical target organ damage in subjects with different components of metabolic syndrome. Clinical and Experimental Hypertension. 2018;40 (5):421-426. IF 1,789. Access link: https://www.tandfonline.com/doi/full/10.1080/10641963.2017.1384488.

Komajda M, Kerneis M, Tavazzi L, et al. The chronic ischaemic cardiovascular disease ESC pilot registry: results of the six-month follow-up. European Journal of Preventive Cardiology. 2018;25 (4):377-387. IF 1,459. Access link: https://pubmed.ncbi.nlm.nih.gov/29338315/.

Rotar OP, Izimarieva DV, Erina AM, et al. Prevalence of cardiovascular risk factors among teachers of Saint Petersburg universities. Профилактическая медицина. 2018;21 (6):42-49. IF 1,066. Access link: https://www.researchgate.net/publication/330898088_Prevalence_of_cardiovascular_risk_factors_among_teachers_of_Saint_Petersburg_universities.

2017 

Shlyakhto E. Russian cardiovascular days 2017. European Heart Journal. 2017;38 (25):1945–1946. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/38/25/1945/3903142.

Baumgartner H, Bax JJ, De Bonis M, et al. 2017 ESC/EACTS guidelines for the management of valvular heart disease. European Heart Journal. 2017:38 (36):2739–2786. IF 24,889. Access link: https://academic.oup.com/eurheartj/article/38/36/2739/4095039.

Rotar O, Boyarinova M, Orlov A, et al. Metabolically healthy obese and metabolically unhealthy non-obese phenotypes in a Russian population. European Journal of Epidemiology. 2017;32 (3):251-254. IF 7,135. Access link: https://pubmed.ncbi.nlm.nih.gov/28039558/.

Mamontov O, Krasnikova T, Volynsky M, et al. Position-dependent changes of blood flow in carotid arteries assessed by camera-based photoplethysmography. Clinical Autonomic Research. 2017;27 (5):323. IF 2,76. Access link: https://www.researchgate.net/publication/321482429_Position-dependent_changes_of_blood_flow_in_carotid_arteries_assessed_by_camera-based_photoplethysmography.

Trukshina MA, Lyasnikova EA, Galenko VL, et al. First steps and experience in cardiac contractility modulation in patients with heart failure with reduced ejection fraction: looking into the near future. European Journal of Heart Failure Supplements. 2017;19 (S1):116. IF 1,655. Access link: https://esc365.escardio.org/Congress/Heart-Failure-2017-4th-World-Congress-on-Acute-Heart-Failure/Poster-Session-1-Devices-CRT-ICD-Surgery/152833-first-steps-and-experience-in-cardiac-contractility-modulation-in-patients-with-heart-failure-with-reduced-ejection-fraction-looking-into-the-near-future.

Alfonso F, Adamyan K, Artigou JY, et al. Data sharing: a new editorial initiative of the international committee of medical journal editors. Implications for the editors´ network. Arquivos Brasileiros de Cardiologia. 2017;108 (5):390-394. IF 1,318. Access link: https://www.sciencedirect.com/science/article/pii/S1110260817300728.

Patents

Patent for invention RU 2677280 C1, “Method for diagnosing multivessel atherosclerotic coronary artery disease in CAD patients with abdominal obesity”
Authors: E.A. Polyakova, M.I. Zaraisky, O.D. Belyaeva, O.A. Berkovich, E.I. Baranova, E.V. Shlyakhto

Patent for invention RU 2670689 C1, “Method for predicting cardiovascular complications in CAD patients”
Authors: E.V. Shlyakhto, E.G. Sergeeva, O.A. Berkovich, Zh.I. Ionova, E.I. Baranova

Discoveries

“Pattern of baroreflex regulation of blood pressure in mammals under emotional stress”
Authors: A.V. Valdman, V.A. Tsyrlin, E.V. Shlyakhto, V.S. Eremeev, M.F. Bravkov, M.G. Pliss, B.G. Bershadsky, R.S. Khrustaleva, Yu.V. Scherbin.
Certificate for Discovery – Diploma No. 116 dated May 21, 1999.

“Pattern of blood pressure regulation in humans and animals under the influence of baroreflex”
Authors: V.A. Almazov, E.V. Shlyakhto, N.V. Kuzmenko, M.G. Pliss, V.A. Tsyrlin, Yu.I. Scherbin
Certificate for Discovery – Diploma No. 400 dated September 15, 2010