Laboratory for Surgery of Metabolic Disorders

 
Alexander Neumark, MD, PhD
Head of Laboratory

The Research Laboratory for Surgery of Metabolic Disorders was established as part of the Institute of Endocrinology.

Its major specialization is bariatric and endocrine surgery.

 Major research areas:

  • Studying the possibility of predicting the outcomes of bariatric surgery.
  • Justifying and assessing the systemic effects of bariatric surgery on the components of metabolic syndrome.
  • Developing and implementing the concept of personalized medicine based on the assessment of genetically determined and phenotypic changes using clinical expert systems in the surgical treatment of patients with metabolic syndrome and type 2 DM.
  • Substantiating the surgical methods for incretin disorders in type 2 DM in patients with a BMI of less than 35 kg/m2.
  • Preventing and developing new methods for the treatment of instrumental suture failure in longitudinal gastric resection.
  • Studying the mechanisms for correction of obesity and metabolic disorders using gut microflora.
  • Transplanting pancreatic β-cells.

Collaboration

  • Laboratory of Molecular Cardiology (University of Zurich, Switzerland), the Russian-Swiss programme “Comparative assessment of the impact of bariatric surgery (longitudinal gastric resection and gastric bypass surgery) on the level of intestinal hormones, endothelial function and dyslipidemia”;
  • Digestion Laboratory of the Pavlov Institute of Physiology – studying the impact of bariatric surgery on the change in glucose transport in the gastrointestinal tract;
  • Laboratory of Immunology and Cellular Biotechnology, Innovative Park, Immanuel Kant Baltic Federal University – ongoing research to study the features of the functional activity of encapsulated insulin-producing cells and MSCs of various origins.

Training and education

In 2015 and 2016, the Laboratory held an annual scientific and practical workshop accredited by the Russian Society of Surgeons and the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) – Surgical Treatment of Obesity and Metabolic Disorders.